|KOSIK - Live at WCBN - KOSIK|
It was warm June night, and this WCBN show was sandwiched between two disastrous live shows. What happened this night, we can't explain, something was in the air, or the vibe was right. We had decided that on this night, we were going to perform without the help of the laptop, so the first part of the recording is completely and totally with acoustic guitars, and trap drums, with the exception of an underlying drone that Jim Owens recommended for the laptop...
Keywords: Matt Borghi; KOSIK; WCBN; IDM; Acoustic; Electronic; Michael Kirson-Goldapper; Ann Arbor; Jim Owens; Chris Stecker
|KOSIK - Removable Pieces [kpu039] - KOSIK|
KOSIK is the project of Matt Borghi and Michael Kirson-Goldapper. Raised on the periphery of Detroit, the two life-long friends were exposed to all kinds of music, much of which has been rolled up into their KOSIK project. While the KOSIK project is relatively new, Michael and Matt have been working together for the better part of a decade on a variety of projects, musical and otherwise. KOSIK is the first collaborative project that Michael and Matt have allowed to see the light of day...
Downloads: 2,505 (1 review)
|Plastic Piano and Slow Kid - KOSIK|
KOSIK's Plastic Piano and Slow Kid, sometimes called Toy Piano and Slow Kid was a demo recording. Matt Borghi and Michael Kirson-Goldapper after having done a great deal of solo work in and around the Detroit-area, these two lifelong friends decided to embark on a musical project. They set about doing this recording in the dark months of November and December 2003. Conceived one night as the two drove up from Cleveland after playing a show, KOSIK almost immediately gained folk's attention...
Keywords: Matt Borghi, KOSIK, Michael Goldapper, IDM, Ambient, Kikapu, Ann Arbor, Detroit, East Lansing, Michigan, Ghostly International, Twine, KILN, Lusine
|Back to Basics: Live at WCBN - Kosik|
|Plastic Piano & Slow Kid - Kosik|
|Removable Pieces - Kosik|
|KOSIK - Fastas [pls002] - KOSIK|
Proving "fusion" is not always a dirty word. Matthew Borghi and Michael Kirson-Goldapper are KOSIK. With releases on Ghostly Int'l, Kikapu, and a long player scheduled later this year on Simballrec, positive rumours about this diverse sound seem to be spreading quickly. For Please Do Something, the two childhood friends offer Fastas - a three track EP that treads into and out of waters charted by the likes of Air and Radiohead...
Keywords: Indie; Electronic
|Tiem Parade - Kosik|
|Exploring the early origins of the synapse by comparative genomics. (Volume 5) - Kosik, Kenneth S.|
This article is from Biology Letters, volume 5.AbstractOne set of evolutionary features that has received less attention than the evolution of genes or species is the evolution of cellular machines, the self-contained structures in cells with dedicated functions. Here I suggest that domain expansion through shuffling, duplication, and changes in protein expression level are critical drivers in the evolution of cellular machines...
|Tiem Parade - Matt Borghi/KOSIK|
This would have been Matt Borghi's first solo release in almost two years, at it's release date of Spring 2003, but then Matt's KOSIK collaborator Michael Goldapper got a hold of it, and mixed it into an ambient IDM collage of kaleidoscopic sounds and moods. It's all about you. Check out the rest of the KOSIK catalog here at the Archive, and also Matt Borghi at http://www.mattborghi.com.
Keywords: Matt Borghi, KOSIK, Michael Goldapper, IDM, Ambient, Kikapu, Ann Arbor, Detroit, East Lansing, Michigan
|MicroRNAs: regulators of oncogenesis and stemness. (Volume 6) - Papagiannakopoulos, Thales|
This article is from BMC Medicine, volume 6.AbstractMicroRNAs (miRNAs) are essential post-transcriptional regulators that determine cell identity and fate. Aberrant expression of miRNAs can lead to diseases, including cancer. Expression of many miRNAs in the de-differentiated brain tumor cancer stem cells resembles that of neural stem cells. In this issue of BMC Medicine, Silber et al provide evidence of the expression of such miRNAs and their potential to mediate differentiation in both stem ce...
|Quantum walks with random phase shifts - Jozef Kosik|
We investigate quantum walks in multiple dimensions with different quantum coins. We augment the model by assuming that at each step the amplitudes of the coin state are multiplied by random phases. This model enables us to study in detail the role of decoherence in quantum walks and to investigate the quantum-to-classical transition. We also provide classical analogues of the quantum random walks studied...
|Quantum Parrondo's game with random strategies - J. Kosik|
We present a quantum implementation of Parrondo's game with randomly switched strategies using 1) a quantum walk as a source of ``randomness'' and 2) a completely positive (CP) map as a randomized evolution. The game exhibits the same paradox as in the classical setting where a combination of two losing strategies might result in a winning strategy. We show that the CP-map scheme leads to significantly lower net gain than the quantum walk scheme.
|Statistical analysis of dendritic spine distributions in rat hippocampal cultures. (Volume 14) - Jammalamadaka, Aruna|
This article is from BMC Bioinformatics, volume 14.AbstractBackground: Dendritic spines serve as key computational structures in brain plasticity. Much remains to be learned about their spatial and temporal distribution among neurons. Our aim in this study was to perform exploratory analyses based on the population distributions of dendritic spines with regard to their morphological characteristics and period of growth in dissociated hippocampal neurons...
|Incidence of Common Preleukemic Gene Fusions in Umbilical Cord Blood in Slovak Population. (Volume 9) - Skorvaga, Milan|
This article is from PLoS ONE, volume 9.AbstractThe first event in origination of many childhood leukemias is likely the presence of preleukemic clone (transformed hematopoietic stem/progenitor cells with preleukemic gene fusions (PGF)) in newborn. Thus, the screening of umbilical cord blood (UCB) for PGF may be of high importance for developing strategies for childhood leukemia prevention and treatment...
|Neural Development Under Conditions of Spaceflight - Kosik, Kenneth S.|
One of the key tasks the developing brain must learn is how to navigate within the environment. This skill depends on the brain's ability to establish memories of places and things in the environment so that it can form cognitive maps. Earth's gravity defines the plane of orientation of the spatial environment in which animals navigate, and cognitive maps are based on this plane of orientation. Given that experience during early development plays a key role in the development of other aspects of...
Keywords: THERMAL CONTROL COATINGS; FRACTURE STRENGTH; FATIGUE (MATERIALS); DEFORMATION; SINTERING; ZIRCONIUM OXIDES; STRESS-STRAIN RELATIONSHIPS
|Transcriptome profiling of the demosponge Amphimedon queenslandica reveals genome-wide events that accompany major life cycle transitions. (Volume 13) - Conaco, Cecilia|
This article is from BMC Genomics, volume 13.AbstractBackground: The biphasic life cycle with pelagic larva and benthic adult stages is widely observed in the animal kingdom, including the Porifera (sponges), which are the earliest branching metazoans. The demosponge, Amphimedon queenslandica, undergoes metamorphosis from a free-swimming larva into a sessile adult that bears no morphological resemblance to other animals...
|Deep annotation of mouse iso-miR and iso-moR variation. (Volume 40) - Zhou, Hongjun|
This article is from Nucleic Acids Research, volume 40.AbstractWith a dataset of more than 600 million small RNAs deeply sequenced from mouse hippocampal and staged sets of mouse cells that underwent reprogramming to induced pluripotent stem cells, we annotated the stem–loop precursors of the known miRNAs to identify isomoRs (miRNA-offset RNAs), loops, non-preferred strands, and guide strands. Products from both strands were readily detectable for most miRNAs...
|Reduction in psychotic symptoms as a predictor of patient satisfaction with antipsychotic medication in schizophrenia: Data from a randomized double-blind trial. (Volume 6) - Gharabawi, Georges M|
This article is from BMC Psychiatry, volume 6.AbstractBackground: Patient satisfaction with antipsychotic treatment is important. Limited evidence suggests that satisfaction is associated with symptom improvement and compliance. Predictors of patient satisfaction with antipsychotic medication were examined in a study of patients with a recent exacerbation of schizophrenia. Methods: Data are from a randomized, double-blind trial comparing risperidone (n = 152), quetiapine (n = 156), and placebo (...
|Staged miRNA re-regulation patterns during reprogramming. (Volume 14) - Henzler, Christine M|
This article is from Genome Biology, volume 14.AbstractBackground: MiRNAs often operate in feedback loops with transcription factors and represent a key mechanism for fine-tuning gene expression. In transcription factor-induced reprogramming, miRNAs play a critical role; however, detailed analyses of miRNA expression changes during reprogramming at the level of deep sequencing have not been previously reported...
|MicroRNA profiling of the murine hematopoietic system. (Volume 6) - Monticelli, Silvia|
This article is from Genome Biology, volume 6.AbstractThe first report of systematic miRNA profiling in cells of the hematopoietic system suggests that, in addition to regulating commitment to particular cellular lineages, miRNAs might have a general role in cell differentiation and cell identity.
|Genetic Correction of Tauopathy Phenotypes in Neurons Derived from Human Induced Pluripotent Stem Cells. (Volume 1) - Fong, Helen|
This article is from Stem Cell Reports, volume 1.AbstractTauopathies represent a group of neurodegenerative disorders characterized by the accumulation of pathological TAU protein in brains. We report a human neuronal model of tauopathy derived from induced pluripotent stem cells (iPSCs) carrying a TAU-A152T mutation. Using zinc-finger nuclease-mediated gene editing, we generated two isogenic iPSC lines: one with the mutation corrected, and another with the homozygous mutation engineered...
|Pooling/bootstrap-based GWAS (pbGWAS) identifies new loci modifying the age of onset in PSEN1 p.Glu280Ala Alzheimer's disease. (Volume 18) - Velez, J I|
This article is from Molecular Psychiatry, volume 18.AbstractThe literature on GWAS (genome-wide association studies) data suggests that very large sample sizes (for example, 50,000 cases and 50,000 controls) may be required to detect significant associations of genomic regions for complex disorders such as Alzheimer's disease (AD). Because of the challenges of obtaining such large cohorts, we describe here a novel sequential strategy that combines pooling of DNA and bootstrapping (pbGWAS) in or...